Effects of a traditionally-dosed creatine supplementation protocol and resistance training on the skeletal muscle uptake and whole-body metabolism and retention of creatine in males
نویسندگان
چکیده
Background A typical oral creatine supplementation regimen involving a 5-7 day “loading phase” of 20-25 grams/day followed by a “maintenance phase” of 5-7 grams/day is typically considered as necessary to adequately saturate skeletal muscle as a lesser dose of creatine is insufficient in doing so. This rationale also assumes that the majority, if not all, of the creatine ingested at this dosage is fully utilized by skeletal muscle as a phosphate reservoir in which to re-synthesize ATP during high-intensity, short-term exercise. The purpose of this study was simply to determine the effects of this “typical” creatine dosing strategy previously mentioned on skeletal muscle creatine uptake as well as the whole-body metabolism and retention of creatine in males while engaged in resistance training.
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